The following reseaches were carried out to investigate the biological roles . a reseach by hinter showed that igg ak auto ab opsonized insoluable aggregates of keratin intermediate filament ( kif ) Hinter等通过研究发现igg型akautoah对不溶性的角蛋白中间丝（ keratiintermediateilament ， kif ）凝集物具有调理吞噬作用。
